Città di Castello to Busto Arsizio trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Arezzo, Rimini, Firenze S. M. Novella and arrive at Busto Arsizio, Milano Centrale, Milano Porta Garibaldi every 7 minutes on average. If travelling with ItaloTreno, you need to know the Città di Castello to Busto Arsizio train schedule: the first train leaves at 08:25, while the last ride is at 21:25. ItaloTreno offers 12 direct trains between these two cities. There are also Trenitalia trains from Città di Castello to Busto Arsizio; you can compare ItaloTreno and Trenitalia with Wanderio, so that you find the best fare in a quick and simple way. A Città di Castello to Busto Arsizio train ticket with Trenitalia costs 18.25 € on average and you can find rides from 00:47 to 20:42. If you need to travel this week, prices start from 35.75€ to a maximum price of 51.90€. When booking your train ticket a few weeks in advance though, you can find low cost trains from Città di Castello to Busto Arsizio with fares starting from 18.25€, saving up to 61%.