Città di Castello to Caltagirone trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Arezzo and arrive at Caltagirone every about 12 hours on average. If travelling with Trenitalia, you need to know the Città di Castello to Caltagirone train schedule: the first train leaves at 19:02, while the last ride is at 19:02. A Città di Castello to Caltagirone train cost about 203.5 €. But how long is the train ride from Città di Castello to Caltagirone? Your journey takes about 20 hours on average.