Città di Castello to Castelvetrano trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Arezzo and arrive at Castelvetrano every about 12 hours on average. If travelling with Trenitalia, you need to know the Città di Castello to Castelvetrano train schedule: the first train leaves at 19:02, while the last ride is at 19:02. A Città di Castello to Castelvetrano train cost about 137.35 €. But how long is the train ride from Città di Castello to Castelvetrano? Your journey takes about 18 hours on average.