Colleferro to Mestre trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Colleferro-Segni-Paliano and arrive at Venezia Mestre every 60 minutes on average. If travelling with Trenitalia, you need to know the Colleferro to Mestre train schedule: the first train leaves at 06:24, while the last ride is at 21:41. A Colleferro to Mestre train cost about 51.6 €. But how long is the train ride from Colleferro to Mestre? Your journey takes about 6 hours on average.