Colleferro to Syracuse trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Colleferro-Segni-Paliano and arrive at Siracusa every about 2 hours on average. If travelling with Trenitalia, you need to know the Colleferro to Syracuse train schedule: the first train leaves at 05:33, while the last ride is at 20:52. A Colleferro to Syracuse train cost about 62.6 €. But how long is the train ride from Colleferro to Syracuse? Your journey takes about 13 hours on average.