Comiso to Castelvetrano trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Comiso and arrive at Castelvetrano every about 6 hours on average. If travelling with Trenitalia, you need to know the Comiso to Castelvetrano train schedule: the first train leaves at 20:24, while the last ride is at 20:24. A Comiso to Castelvetrano train cost about 17.6 €. But how long is the train ride from Comiso to Castelvetrano? Your journey takes about 17 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Comiso to Castelvetrano and find low cost tickets starting from 19 €!