Comiso to Palermo trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 2 daily rides to get from Comiso to Palermo. The first train to Palermo leaves from Comiso at 04:40 and the last train departs at 12:48. If you choose a local train the trip lasts on average 08:12 hours. For your trip from Comiso to Palermo by train you can choose to leave from one of Comiso main stations: Comiso On Wanderio you can compare all schedules, fares and railway companies to Palermo and book the best itinerary starting from Comiso.