Comiso to Palermo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Comiso and arrive at Palermo Notarbartolo every about 6 hours on average. If travelling with Trenitalia, you need to know the Comiso to Palermo train schedule: the first train leaves at 12:48, while the last ride is at 12:48. A Comiso to Palermo train cost about 13.9 €. But how long is the train ride from Comiso to Palermo? Your journey takes about 9 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Comiso to Palermo and find low cost tickets starting from 15 €!