Comiso to Varese trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Comiso and arrive at Varese every about 4 hours on average. If travelling with Trenitalia, you need to know the Comiso to Varese train schedule: the first train leaves at 07:09, while the last ride is at 18:22. A Comiso to Varese train cost about 137.3 €. But how long is the train ride from Comiso to Varese? Your journey takes about 2 hours on average.