Como to Alpignano trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Como S. Giovanni and arrive at Alpignano every 60 minutes on average. If travelling with Trenitalia, you need to know the Como to Alpignano train schedule: the first train leaves at 06:36, while the last ride is at 19:13. A Como to Alpignano train cost about 14.65 €. But how long is the train ride from Como to Alpignano? Your journey takes about 3 hours on average.