Como to Comiso trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Como S. Giovanni and arrive at Comiso every about 6 hours on average. If travelling with Trenitalia, you need to know the Como to Comiso train schedule: the first train leaves at 17:13, while the last ride is at 19:13. A Como to Comiso train cost about 97.1 €. But how long is the train ride from Como to Comiso? Your journey takes about 10 hours on average.