Como to Niscemi trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Como S. Giovanni and arrive at Niscemi every about 6 hours on average. If travelling with Trenitalia, you need to know the Como to Niscemi train schedule: the first train leaves at 17:13, while the last ride is at 19:13. A Como to Niscemi train cost about 118.85 €. But how long is the train ride from Como to Niscemi? Your journey takes about 12 hours on average.