Crema to Caltanissetta trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Crema and arrive at Caltanissetta Centrale every about 4 hours on average. If travelling with Trenitalia, you need to know the Crema to Caltanissetta train schedule: the first train leaves at 17:25, while the last ride is at 19:25. A Crema to Caltanissetta train cost about 131.3 €. But how long is the train ride from Crema to Caltanissetta? Your journey takes about 6 hours on average.