Crema to Castelvetrano trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Crema and arrive at Castelvetrano every about 4 hours on average. If travelling with Trenitalia, you need to know the Crema to Castelvetrano train schedule: the first train leaves at 17:25, while the last ride is at 19:25. A Crema to Castelvetrano train cost about 77.65 €. But how long is the train ride from Crema to Castelvetrano? Your journey takes about 8 hours on average.