Crema to Comiso trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Crema and arrive at Comiso every about 6 hours on average. If travelling with Trenitalia, you need to know the Crema to Comiso train schedule: the first train leaves at 17:25, while the last ride is at 18:25. A Crema to Comiso train cost about 78.5 €. But how long is the train ride from Crema to Comiso? Your journey takes about 11 hours on average.