Cremona to Castelvetrano trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Cremona and arrive at Castelvetrano every about 2 hours on average. If travelling with Trenitalia, you need to know the Cremona to Castelvetrano train schedule: the first train leaves at 06:58, while the last ride is at 17:30. A Cremona to Castelvetrano train cost about 114.95 €. But how long is the train ride from Cremona to Castelvetrano? Your journey takes about 13 hours on average.