Cremona to Marsala trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Napoli Centrale and arrive at Spagnuola every about 12 hours on average. If travelling with Trenitalia, you need to know the Cremona to Marsala train schedule: the first train leaves at 23:53, while the last ride is at 23:53. A Cremona to Marsala train cost about 95.3 €. But how long is the train ride from Cremona to Marsala? Your journey takes about 14 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Cremona to Marsala and find low cost tickets starting from 61 €!