Cremona to Niscemi trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Cremona and arrive at Niscemi every about 12 hours on average. If travelling with Trenitalia, you need to know the Cremona to Niscemi train schedule: the first train leaves at 17:30, while the last ride is at 17:30. A Cremona to Niscemi train cost about 81.6 €. But how long is the train ride from Cremona to Niscemi? Your journey takes about 4 hours on average.