Cremona to Palermo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Cremona and arrive at Palermo Notarbartolo every about 2 hours on average. If travelling with Trenitalia, you need to know the Cremona to Palermo train schedule: the first train leaves at 15:23, while the last ride is at 17:30. A Cremona to Palermo train cost about 108.8 €. But how long is the train ride from Cremona to Palermo? Your journey takes about 20 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Cremona to Palermo and find low cost tickets starting from 47 €!