Cremona to Palermo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Cremona and arrive at Palermo Notarbartolo every about 2 hours on average. If travelling with Trenitalia, you need to know the Cremona to Palermo train schedule: the first train leaves at 15:23, while the last ride is at 17:30. A Cremona to Palermo train cost about 108.8 €. But how long is the train ride from Cremona to Palermo? Your journey takes about 20 hours on average.