Desenzano del Garda to Caltanissetta trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Desenzano del Garda-Sirmione and arrive at Caltanissetta Centrale every about 2 hours on average. If travelling with Trenitalia, you need to know the Desenzano del Garda to Caltanissetta train schedule: the first train leaves at 06:51, while the last ride is at 23:52. A Desenzano del Garda to Caltanissetta train cost about 111.45 €. But how long is the train ride from Desenzano del Garda to Caltanissetta? Your journey takes about 12 hours on average.