Desenzano del Garda to Marsala trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Desenzano del Garda-Sirmione and arrive at Mozia-Birgi every about 4 hours on average. If travelling with Trenitalia, you need to know the Desenzano del Garda to Marsala train schedule: the first train leaves at 17:07, while the last ride is at 18:22. A Desenzano del Garda to Marsala train cost about 162.25 €. But how long is the train ride from Desenzano del Garda to Marsala? Your journey takes about 15 hours on average.