Desio to Alpignano trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Desio and arrive at Alpignano every 60 minutes on average. If travelling with Trenitalia, you need to know the Desio to Alpignano train schedule: the first train leaves at 07:02, while the last ride is at 07:02. A Desio to Alpignano train cost about 36.1 €. But how long is the train ride from Desio to Alpignano? Your journey takes about 3 hours on average.