To get from Desio a Casarano by train you can catch one of the 37 trains that everyday travel between Desio and Lecce, the closest station to the city. For your trip from Desio to Lecce by train you can choose to leave from one of Desio main stations: Desio, Salerno If travelling with Trenitalia, you need to know the Desio to Lecce train schedule: the first train leaves at 07:02, while the last ride is at 17:47. A Desio to Lecce train cost about 19.85 €. But how long is the train ride from Desio to Lecce? Your journey takes about 7 hours on average.