Desio to Quattromiglia trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Desio and arrive at Castiglione Cosentino every 60 minutes on average. If travelling with Trenitalia, you need to know the Desio to Quattromiglia train schedule: the first train leaves at 06:09, while the last ride is at 22:15. A Desio to Quattromiglia train cost about 66.4 €. But how long is the train ride from Desio to Quattromiglia? Your journey takes about 12 hours on average.