Desio to Ragusa trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Desio and arrive at Ragusa every about 4 hours on average. If travelling with Trenitalia, you need to know the Desio to Ragusa train schedule: the first train leaves at 15:54, while the last ride is at 19:09. A Desio to Ragusa train cost about 124.45 €. But how long is the train ride from Desio to Ragusa? Your journey takes about 13 hours on average.