Domodossola to Agrigento trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Domodossola and arrive at Agrigento Bassa every about 6 hours on average. If travelling with Trenitalia, you need to know the Domodossola to Agrigento train schedule: the first train leaves at 16:54, while the last ride is at 16:54. A Domodossola to Agrigento train cost about 107.0 €. But how long is the train ride from Domodossola to Agrigento? Your journey takes about 11 hours on average.