Domodossola to Catania trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Domodossola and arrive at Catania Centrale every about 3 hours on average. If travelling with Trenitalia, you need to know the Domodossola to Catania train schedule: the first train leaves at 04:54, while the last ride is at 16:54. A Domodossola to Catania train cost about 89.8 €. But how long is the train ride from Domodossola to Catania? Your journey takes about 18 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Domodossola to Catania and find low cost tickets starting from 55 €!