Domodossola to Molfetta trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Domodossola and arrive at Molfetta every 60 minutes on average. If travelling with Trenitalia, you need to know the Domodossola to Molfetta train schedule: the first train leaves at 06:51, while the last ride is at 18:54. A Domodossola to Molfetta train cost about 72.5 €. But how long is the train ride from Domodossola to Molfetta? Your journey takes about 12 hours on average.