Domodossola to Partinico trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Domodossola and arrive at Partinico every about 12 hours on average. If travelling with Trenitalia, you need to know the Domodossola to Partinico train schedule: the first train leaves at 16:54, while the last ride is at 16:54. A Domodossola to Partinico train cost about 249.15 €. But how long is the train ride from Domodossola to Partinico? Your journey takes about 19 hours on average.