Domodossola to Trieste trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Domodossola and arrive at Trieste Centrale every about 2 hours on average. If travelling with Trenitalia, you need to know the Domodossola to Trieste train schedule: the first train leaves at 04:54, while the last ride is at 16:54. A Domodossola to Trieste train cost about 64.0 €. But how long is the train ride from Domodossola to Trieste? Your journey takes about 7 hours on average.