Domodossola to Vasto trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Domodossola and arrive at Porto di Vasto every 60 minutes on average. If travelling with Trenitalia, you need to know the Domodossola to Vasto train schedule: the first train leaves at 06:51, while the last ride is at 18:54. A Domodossola to Vasto train cost about 64.9 €. But how long is the train ride from Domodossola to Vasto? Your journey takes about 10 hours on average.