Empoli to Agrigento trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Empoli and arrive at Agrigento Bassa every about 4 hours on average. If travelling with Trenitalia, you need to know the Empoli to Agrigento train schedule: the first train leaves at 01:15, while the last ride is at 22:33. A Empoli to Agrigento train cost about 76.6 €. But how long is the train ride from Empoli to Agrigento? Your journey takes about 19 hours on average.