To get from Empoli a Casarano by train you can catch one of the 38 trains that everyday travel between Empoli and Lecce, the closest station to the city. For your trip from Empoli to Lecce by train you can choose to leave from one of Empoli main stations: Empoli, Salerno If travelling with Trenitalia, you need to know the Empoli to Lecce train schedule: the first train leaves at 06:18, while the last ride is at 21:21. A Empoli to Lecce train cost about 19.85 €. But how long is the train ride from Empoli to Lecce? Your journey takes about 10 hours on average.