Empoli to Enna trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Empoli and arrive at Enna every about 4 hours on average. If travelling with Trenitalia, you need to know the Empoli to Enna train schedule: the first train leaves at 01:15, while the last ride is at 22:33. A Empoli to Enna train cost about 121.15 €. But how long is the train ride from Empoli to Enna? Your journey takes about 18 hours on average.