Empoli to Marsala trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Empoli and arrive at Mozia-Birgi every about 12 hours on average. If travelling with Trenitalia, you need to know the Empoli to Marsala train schedule: the first train leaves at 22:33, while the last ride is at 22:33. A Empoli to Marsala train cost about 89.05 €. But how long is the train ride from Empoli to Marsala? Your journey takes about 23 hours on average.