Empoli to Varese trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Empoli and arrive at Varese every 60 minutes on average. If travelling with Trenitalia, you need to know the Empoli to Varese train schedule: the first train leaves at 06:35, while the last ride is at 19:21. A Empoli to Varese train cost about 53.7 €. But how long is the train ride from Empoli to Varese? Your journey takes about 4 hours on average.