Empoli to Vicenza trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Empoli and arrive at Vicenza every 60 minutes on average. If travelling with Trenitalia, you need to know the Empoli to Vicenza train schedule: the first train leaves at 08:32, while the last ride is at 19:32. A Empoli to Vicenza train cost about 29.65 €. But how long is the train ride from Empoli to Vicenza? Your journey takes about 3 hours on average.