Enna to Messina trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Enna and arrive at Messina Centrale every about 12 hours on average. If travelling with Trenitalia, you need to know the Enna to Messina train schedule: the first train leaves at 11:28, while the last ride is at 11:28. A Enna to Messina train cost about 9.7 €. But how long is the train ride from Enna to Messina? Your journey takes about 4 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Enna to Messina and find low cost tickets starting from 10 €!