Enna to Mestre trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Enna and arrive at Venezia Mestre every about 6 hours on average. If travelling with Trenitalia, you need to know the Enna to Mestre train schedule: the first train leaves at 09:21, while the last ride is at 18:42. A Enna to Mestre train cost about 93.35 €. But how long is the train ride from Enna to Mestre? Your journey takes about 18 hours on average.