Fano to Syracuse trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Fano and arrive at Siracusa every about 2 hours on average. If travelling with Trenitalia, you need to know the Fano to Syracuse train schedule: the first train leaves at 07:08, while the last ride is at 21:17. A Fano to Syracuse train cost about 110.35 €. But how long is the train ride from Fano to Syracuse? Your journey takes about 17 hours on average.