Florence to Alpignano trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Firenze S. M. Novella and arrive at Alpignano every 60 minutes on average. If travelling with Trenitalia, you need to know the Florence to Alpignano train schedule: the first train leaves at 00:40, while the last ride is at 17:45. A Florence to Alpignano train cost about 54.1 €. But how long is the train ride from Florence to Alpignano? Your journey takes about 4 hours on average.