Florence to Marsala trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Firenze S. M. Novella and arrive at Mozia-Birgi every about 4 hours on average. If travelling with Trenitalia, you need to know the Florence to Marsala train schedule: the first train leaves at 20:04, while the last ride is at 21:57. A Florence to Marsala train cost about 84.45 €. But how long is the train ride from Florence to Marsala? Your journey takes about 21 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Florence to Marsala and find low cost tickets starting from 58 €!