Florence to Noto trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Firenze S. M. Novella and arrive at Noto every about 2 hours on average. If travelling with Trenitalia, you need to know the Florence to Noto train schedule: the first train leaves at 10:19, while the last ride is at 21:57. A Florence to Noto train cost about 93.45 €. But how long is the train ride from Florence to Noto? Your journey takes about 18 hours on average.