To get from Florence to Syracuse by train you can catch one of the 5 trains that everyday travel between these two cities. The first train to Syracuse leaves from Florence at 00:45 and the last train departs at 21:57. The trip by train from Florence to Syracuse last on average 12:41 travelling with high-speed trains (Frecciarossa or Italotreno) If you choose a local train the trip lasts on average 13:47 hours. For your trip from Florence to Syracuse by train you can choose to leave from one of Florence main stations: Firenze S. M. Novella Tickets price depend on the departure time and train type, the most economic train ticket available this week is from € 142 to € 142. The most economic train is Frecciarossa () that departs at 20:04 and arrives in Syracuse at 09:35 at € 142. On Wanderio you can compare all schedules, fares and railway companies to Syracuse and book the best itinerary starting from Florence.