Florence to Vicenza trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Firenze S. M. Novella and arrive at Vicenza every 60 minutes on average. If travelling with Trenitalia, you need to know the Florence to Vicenza train schedule: the first train leaves at 07:34, while the last ride is at 11:00. A Florence to Vicenza train cost about 45.4 €. But how long is the train ride from Florence to Vicenza? Your journey takes about 3 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Florence to Vicenza and find low cost tickets starting from 24 €!