Frascati to Niscemi trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 4 daily rides to get from Frascati to Niscemi. Trains leave from Tor Vergata and arrive at Niscemi every about 3 hours on average. If travelling with Trenitalia, you need to know the Frascati to Niscemi train schedule: the first train leaves at 06:34, while the last ride is at 23:10. A Frascati to Niscemi train cost about 76.15 €. But how long is the train ride from Frascati to Niscemi? Your journey takes about 20 hours on average.