Frosinone to Alpignano trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Frosinone and arrive at Alpignano every about 2 hours on average. If travelling with Trenitalia, you need to know the Frosinone to Alpignano train schedule: the first train leaves at 05:00, while the last ride is at 18:59. A Frosinone to Alpignano train cost about 102.1 €. But how long is the train ride from Frosinone to Alpignano? Your journey takes about 8 hours on average.