Frosinone to Caltagirone trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Frosinone and arrive at Caltagirone every about 6 hours on average. If travelling with Trenitalia, you need to know the Frosinone to Caltagirone train schedule: the first train leaves at 05:41, while the last ride is at 05:41. A Frosinone to Caltagirone train cost about 84.0 €. But how long is the train ride from Frosinone to Caltagirone? Your journey takes about 15 hours on average.