Genoa to Castelvetrano trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Genova Piazza Principe and arrive at Castelvetrano every about 3 hours on average. If travelling with Trenitalia, you need to know the Genoa to Castelvetrano train schedule: the first train leaves at 14:52, while the last ride is at 23:53. A Genoa to Castelvetrano train cost about 76.65 €. But how long is the train ride from Genoa to Castelvetrano? Your journey takes about 17 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Genoa to Castelvetrano and find low cost tickets starting from 93 €!