Genoa to Mazara del Vallo trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 4 daily rides to get from Genoa to Mazara del Vallo. Trains leave from Genova Piazza Principe and arrive at Mazara del Vallo every about 3 hours on average. If travelling with Trenitalia, you need to know the Genoa to Mazara del Vallo train schedule: the first train leaves at 14:52, while the last ride is at 21:49. A Genoa to Mazara del Vallo train cost about 87.5 €. But how long is the train ride from Genoa to Mazara del Vallo? Your journey takes about 17 hours on average.