Genoa to Trapani trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Genova Piazza Principe and arrive at Trapani every about 2 hours on average. If travelling with Trenitalia, you need to know the Genoa to Trapani train schedule: the first train leaves at 14:52, while the last ride is at 23:53. A Genoa to Trapani train cost about 79.4 €. But how long is the train ride from Genoa to Trapani? Your journey takes about 18 hours on average.